Combination of foot stimulation and tolterodine treatment eliminates bladder overactivity in cats
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چکیده
منابع مشابه
Inhibition of bladder overactivity by duloxetine in combination with foot stimulation or WAY-100635 treatment in cats.
The purpose of this study was to determine whether duloxetine [a serotonin (5-HT)-norepinephrine reuptake inhibitor] combined with transcutaneous foot stimulation or WAY-100635 (a 5-HT1A antagonist) can enhance inhibition of bladder overactivity in cats. Cystometrograms were performed on eight cats under α-chloralose anesthesia by infusing saline and then 0.25% acetic acid (AA) to induce bladde...
متن کاملRe: inhibition of bladder overactivity by a combination of tibial neuromodulation and tramadol treatment in cats.
Our recent study in cats revealed that inhibition of bladder overactivity by tibial nerve stimulation (TNS) depends on the activation of opioid receptors. TNS is a minimally invasive treatment for overactive bladder (OAB), but its efficacy is low. Tramadol (an opioid receptor agonist) is effective in treating OAB but elicits significant adverse effects. This study was to determine if a low dose...
متن کاملInhibition of bladder overactivity by a combination of tibial neuromodulation and tramadol treatment in cats
Fan Zhang, Abhijith D. Mally, P. Dafe Ogagan, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat, and Changfeng Tai Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Urology, China Rehabilitation Research Center, School of Rehabilitation Medicine, Capital Medical University, Beijing, China; and Department of Pharmacology and Chemical Biology, U...
متن کاملRole of µ, κ, and δ opioid receptors in tibial inhibition of bladder overactivity in cats.
In α-chloralose anesthetized cats, we examined the role of opioid receptor (OR) subtypes (µ, κ, and δ) in tibial nerve stimulation (TNS)-induced inhibition of bladder overactivity elicited by intravesical infusion of 0.25% acetic acid (AA). The sensitivity of TNS inhibition to cumulative i.v. doses of selective OR antagonists (cyprodime for µ, nor-binaltorphimine for κ, or naltrindole for δ ORs...
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ژورنال
عنوان ژورنال: Neurourology and Urodynamics
سال: 2013
ISSN: 0733-2467
DOI: 10.1002/nau.22479